The Effect of NELL1 and Bone Morphogenetic Protein-2 on Calvarial Bone Regeneration
نویسندگان
چکیده
منابع مشابه
The effect of freeze-dried bone allograft and partially demineralized freeze-dried bone allograft on regeneration of rabbit calvarial bone defects: A Histological and histomorphometric study
Background and Aims: Reconstruction of osseous defects is one of the ideal goals of periodontal treatments and dental implant therapy. Different biomaterials have been used for this purpose and many studies have tried to compare and introduce the best ones. The present study aimed to evaluate the effect of PDFDB (Partially Demineralized Freeze-Dried Bone Graft) and FDBA (Freeze Dried Bone Allog...
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BACKGROUND This study aimed to investigate new bone formation using recombinant human bone morphogenetic protein 2 (rhBMP-2) and locally applied bisphosphonate in rat calvarial defects. METHODS Thirty-six rats were studied. Two circular 5 mm diameter bony defect were formed in the calvaria using a trephine bur. The bony defect were grafted with Bio-Oss® only (group 1, n = 9), Bio-Oss® wetted ...
متن کاملInkjet-based biopatterning of bone morphogenetic protein-2 to spatially control calvarial bone formation.
The purpose of this study was to demonstrate spatial control of osteoblast differentiation in vitro and bone formation in vivo using inkjet bioprinting technology and to create three-dimensional persistent bio-ink patterns of bone morphogenetic protein-2 (BMP-2) and its modifiers immobilized within microporous scaffolds. Semicircular patterns of BMP-2 were printed within circular DermaMatrix hu...
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PURPOSE Bone Morphogenetic Protein-2 (BMP-2) may offer the potential to enhance allograft-host osseous union in limb-salvage surgery following osteosarcoma resection. However, there is concern regarding the effect of locally applied BMP-2 on tumor recurrence and metastasis. The purpose of this project was to evaluate the effect of exogenous BMP-2 on osteosarcoma migration and invasion across a ...
متن کاملEffect of osteoconductive hyaluronate hydrogels on calvarial bone regeneration
BACKGROUND Without exploitation of possibly immunogenic and carcinogenic bone morphogenetic protein, we developed simple but clinically feasible artificial bone graft using osteoconductive hyaluronate (HA) hydrogels and bioactive MegaGen synthetic bone (MGSB). METHODS HA hydrogels were synthesized by the crosslinking reaction between carboxyl groups of HA and amine groups of gelatin (GEL). Th...
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ژورنال
عنوان ژورنال: Journal of Oral and Maxillofacial Surgery
سال: 2010
ISSN: 0278-2391
DOI: 10.1016/j.joms.2009.03.066